Dienstag, 19. September 2017

Zusammenarbeit mit Mag. Cornelia Roschger + Hannah Vulcana

Cornelia Roschger, Saskia Neukirchen, Dr. Brigitta Elsässer, Dr. Mario Schubert, Nicole Maeding, Dr. Thomas Verwanger, Prof. Dr. Barbara Krammer and Prof. Dr. Chiara Cabrele
Version of Record online: 19 SEP 2017 | DOI: 10.1002/cmdc.201700537
Thumbnail image of graphical abstract The front cover picture shows a lactam-bridged peptide scaffold that arranges three hydrophobic groups (acetyl, isobutyl, isobutyl) over two helical turns. These groups mimic three-residue hydrophobic patterns of the helical regions of the helix-loop-helix transcription factors Id (inhibitors of DNA binding and cell differentiation). This cyclopeptide, which has micromolar affinity for its Id-protein target, can penetrate the cancer cell membrane, accumulate in the nucleus, and induce cell growth inhibition and cell death in the micromolar range. The superhero was drawn by Hannah Vulcana Kriechbaum + with help from Mag. Cornelia Roschger (www.hannahvulcana.blogspot.com). More information can be found in the Full Paper by Chiara Cabrele et al. on page 1497 in Issue 18, 2017

text online

Sonntag, 10. September 2017

F I T Z "head in the clouds"

Video out now :)


watch out - made by trashed factory

Mittwoch, 6. September 2017

Markus Tremel: Empfehlung in Altmünster


Geschnitzte Kunstwerke - Portraits aus Holz